منابع مشابه
Viral Bcl-2-Mediated Evasion of Autophagy Aids Chronic Infection
c-herpesviruses (cHVs) have developed an interaction with their hosts wherein they establish a life-long persistent infection and are associated with the onset of various malignancies. One critical virulence factor involved in the persistency of murine c-herpesvirus 68 (cHV68) is the viral homolog of the Bcl-2 protein (vBcl-2), which has been implicated to counteract both host apoptotic respons...
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A pirate is a person who buys a legal copy of a copyrighted work and who reproduces it to sell illegal copies. Artists and authors are worried as they do not get the income which is legally theirs. It has been suggested to mark every copy sold with a unique fingerprint, so that any unauthorised copy may be traced back to the source and the pirate who bought it. The fingerprint must be embedded ...
متن کاملBcl-2
Recent findings from our laboratory provide the first indication that overexpression of Bcl-2 in Eµ-myc transgenic cells enhances tumor immunosurveillance by inducing NKG2D ligands. Initial evidence suggests that this model is relevant to human patients. Thus, antitumor therapies that target Bcl-2 harbor the risk of reducing tumor immunogenicity.
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Other names: BAM, BIM, BIM-alpha6, BIM-beta6, BIM-beta7, BOD, BimEL, BimL HGNC (Hugo): BCL2L11 Location: 2q13 Local order: According to GeneLoc and NCBI Map Viewer, genes flanking BCL2L11 in plus strand direction are: ACOXL 2q13 (acyl-Coenzyme A oxidase-like); PAFAH1P2 2q13 (platelet-activating factor acetylhydrolase, isoform Ib, pseudogene 2). Note: BCL2L11/BIM is a BH3-only protein from the B...
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In this issue of Blood, Simon and colleagues provide the first proof that dengue virus (DENV) raids platelets and steals their translational machinery to replicate and produce infectious virus.
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ژورنال
عنوان ژورنال: Nature Reviews Molecular Cell Biology
سال: 2000
ISSN: 1471-0072,1471-0080
DOI: 10.1038/35040037